USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q86U67 USC-OGP 2-DE database:  Q86U67 Q86U67 General information about the entry View entry in simple text format Entry name MANF_HUMAN Primary accession number Q86U67 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Mesencephalic astrocyte-derived neurotrophic factor; AltName: Full=Arginine-rich protein; AltName: Full=Protein ARMET; Flags: Precursor;. Gene name Name=MANF Synonyms=ARMET, ARP Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1330: pI=8.41; Mw=16760 Cross-references UniProtKB/Swiss-Prot P55145; MANF_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name MANF_HUMAN Primary accession number P55145 Secondary accession number(s) Q14CX4 Q86U67 Q96IS4 Sequence was last modified on  May 3, 2011 (version 3) Annotations were last modified on  March 15, 2017 (version 142) Name and origin of the protein Description RecName: Full=Mesencephalic astrocyte-derived neurotrophic factor; AltName: Full=Arginine-rich protein; AltName: Full=Protein ARMET; Flags: Precursor; Gene name Name=MANF Synonyms=ARMET, ARP Encoded on Name=MANF; Synonyms=ARMET, ARP Keywords 3D-structure; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Growth factor; Phosphoprotein; Reference proteome; Secreted; Sialic acid; Signal; Unfolded protein response. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M83751; AAB08753.1; ALT_INIT; mRNA EMBL BT007110; AAP35774.1; -; mRNA EMBL AC092037; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC007282; AAH07282.1; -; mRNA EMBL BC113588; AAI13589.1; ALT_INIT; mRNA EMBL BC113590; AAI13591.1; ALT_INIT; mRNA RefSeq NP_006001.4; NM_006010.5; . UniGene Hs.436446; -; . PDB 2KVD; NMR; -; A=25-182 PDB 2KVE; NMR; -; A=120-182 PDB 2W51; X-ray; 2.80 A; A=25-182 PDBsum 2KVD; -; . PDBsum 2KVE; -; . PDBsum 2W51; -; . ProteinModelPortal P55145; -; . SMR P55145; -; . BioGrid 113621; 10; . IntAct P55145; 4; . MINT MINT-3020834; -; . STRING 9606.ENSP00000432799; -; . iPTMnet P55145; -; . PhosphoSitePlus P55145; -; . BioMuta MANF; -; . DMDM 332278201; -; . OGP P55145; -; . EPD P55145; -; . MaxQB P55145; -; . PaxDb P55145; -; . PeptideAtlas P55145; -; . PRIDE P55145; -; . DNASU 7873; -; . Ensembl ENST00000627526; ENSP00000487450; ENSG00000145050; . GeneID 7873; -; . KEGG hsa:7873; -; . UCSC uc003dbc.4; human; . CTD 7873; -; . DisGeNET 7873; -; . GeneCards MANF; -; . HGNC HGNC:15461; MANF; . HPA HPA011175; -; . MIM 601916; gene; . neXtProt NX_P55145; -; . Orphanet 1333; Familial pancreatic carcinoma; . PharmGKB PA24993; -; . eggNOG KOG4154; Eukaryota; . eggNOG ENOG4111QMZ; LUCA; . HOGENOM HOG000264245; -; . InParanoid P55145; -; . PhylomeDB P55145; -; . TreeFam TF314252; -; . Reactome R-HSA-114608; Platelet degranulation; . EvolutionaryTrace P55145; -; . GeneWiki ARMET; -; . GenomeRNAi 7873; -; . PRO PR:P55145; -; . Proteomes UP000005640; Unplaced; . Bgee ENSG00000145050; -; . CleanEx HS_ARMET; -; . Genevisible P55145; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005783; C:endoplasmic reticulum; IBA:GO_Central; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005615; C:extracellular space; IBA:GO_Central; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0071542; P:dopaminergic neuron differentiation; IBA:GO_Central; . GO GO:0031175; P:neuron projection development; IBA:GO_Central; . GO GO:0002576; P:platelet degranulation; TAS:Reactome; . GO GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW; . Gene3D 1.10.225.10; -; 1; . InterPro IPR019345; Armet_prot; . InterPro IPR011001; Saposin-like; . PANTHER PTHR12990; PTHR12990; 1; . Pfam PF10208; Armet; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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